Postdoctoral Scientist positions are available in the Laboratory of Joshua Burda, PhD within the Center for Neural Science and Medicine (CNSM) and Regenerative Medicine Institute at Cedars-Sinai Medical Center in Los Angeles, California.
As one of the most dynamic and highly renowned medical centers in the world, Cedars-Sinai ranks among the nation's top non-university hospitals for competitive research funding from the National Institutes of Health (NIH), with more than 900 active research projects. This fertile and highly collaborative scientific environment provides an exceptional atmosphere for Postdoctoral research and professional skills training.
The Ideal Candidate will investigate glia-neuron molecular interactions underlying the regenerative plasticity of neural circuits after central nervous system (CNS) injury and in disease. This NIH-funded study has direct and important relevance to patients with traumatic brain injury, spinal cord injury, stroke or neurodegenerative diseases such as multiple sclerosis, in which therapeutically harnessing plasticity of intact neural circuits may be a key to improving outcome and promoting recovery.
Research Aims make use of multiple mouse models of nervous system injury and employ cell type-specific in vivo molecular manipulations, RNA sequencing, mouse transgenics, primary neuron, astrocyte and microglia culture, molecular biology, protein biochemistry, neuroanatomical tract tracing, histology, microscopy, sensorimotor physiology and behavioral assessments.
This is an outstanding opportunity to work with a multidisciplinary group of neuroscientists, neurologists, geneticists and bioinformaticians interested in identifying new therapeutic strategies for stimulating endogenous pathways of CNS repair and recovery. Postdoctoral Scientists in the Burda Lab also benefit from the groups' well-established and ongoing collaborations with neighboring UCLA David Geffen School of Medicine and Brain Research Institute Investigators.
Specifically, the Candidate should have practical experience with:
A range of basic wet lab techniques including molecular biology, nucleic acid and/or protein biochemistry, cell and/or tissue culture.
Disease modeling in rodents. Experience with rodent surgery is preferred, but not required.
Working independently, but in close cooperation and in consultation with the Principal Investigator (PI) to perform routine and complex laboratory procedures.
Developing, adapting, and implementing new research techniques and protocols and analyzing and interpreting data.
Participating in publications and presentations as author or co-author
Assisting in the preparation of grant proposals.
Expectations and Job Duties:
The ideal Candidate is an excellent problem solver that tackles scientific questions and technical hurdles with innovation and inquisitiveness.
Participate in publications and travel to scientific meetings to present research.
Design and perform experiments.
Keep appropriate experimental records and documentation, and analyze results with PI.
May develop, adapt, and implement new research techniques and protocols.
Analyze, interpret, summarize and compile data.
Perform routine and complex laboratory procedures throughout training period.
Operate and maintain equipment and instruments.
Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments and general lab maintenance will be required.
The individual will be expected to function efficiently and cooperatively with a team of faculty, research associates, technicians and students.
Scheduling flexibility is required.
Excellent written and oral communication skills are essential.
Collaborate with PI in preparation of Postdoctoral Fellowship applications.
Since its beginning in 1902, Cedars-Sinai has evolved to meet the healthcare needs of one of the most diverse regions in the nation, continually setting new standards in quality and innovation in patient care, research, teaching and community service. Today, Cedars-Sinai is widely known for its national leadership in transforming healthcare for the benefit of patients.Cedars-Sinai is one of the largest nonprofit academic medical centers in the U.S. with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Clinical programs range from primary care for preventing, diagnosing and treating common conditions to specialized treatments for rare, complex and advanced illnesses. In addition, Cedars-Sinai serves the community through its Medical Network, which includes the highly rated Cedars-Sinai Medical Group and Cedars-Sinai Health Associates. Cedars-Sinai has consistently been named one of America’s Best Hospitals by U.S. News & World Report, has received the National Research Corporation’s Consumer Choice Award 18 years in a row for providing the highest quality medical care in Los Angeles, and has the longest running Magnet desig...nation for nursing excellence in California. Cedars-Sinai is a leader in the clinical care and research of heart disease, cancer and brain disorders, among other areas. Pioneering research achievements include using cardiac stem cells to repair damaged hearts, developing minimally invasive surgical techniques and discovering new types of drugs to target cancer more precisely. Cedars-Sinai also impacts the future of healthcare through education programs that encompass everything from highly competitive medical residency and fellowship programs to a biomedical science and translational medicine PhD program, advanced training for nurses and educational opportunities for allied health professionals. Most notably, Cedars-Sinai demonstrates a longstanding commitment to strengthening the Los Angeles community through wide-ranging programs that improve the health of its most vulnerable residents.