The Northwest MIRECC at the VA Puget Sound in Seattle, WA is seeking an outstanding cellular and molecular post-doctoral scientist with an emphases in neuroscience and/or immunology. The successful candidate will lead the development of translational research projects using animal models of traumatic brain injury to develop testable hypotheses in the clinical research environment. Specific responsibilities will include working synergistically with our internal and external partners to develop, validate and deploy CYTOF, imaging mass cytometry, lightsheet microscopy and biomarker identification methods.
The successful candidate will have a strong background in applying advanced molecular biology & biochemical techniques to answer fundamental questions in the fields of neurotrauma with a track record of both individual and team contributions in solving complex research problems. Strongest consideration will be given to candidates with a proven history of identifying and progressing novel hypotheses forward in discovery research and/or translational settings. Relevant experiences would include familiarity with high-dimensional flow cytometry, CYTOF, single cell transcriptomics, imaging mass cytometry, cell culture and fluorescent microscopy. Bioinformatics expertise is strongly preferred.
The ideal candidate is a self-motivated team player who is willing to push the boundaries of human neuro-immunological research through scientific leadership, individual and team contributions and continuing scholarship covering the ever-changing landscapes of neurotrauma. The successful candidate will also have an established external network in immunology and excellent communication skills that can represent our efforts to our stakeholders.
PhD and/or MD in neuroscience, immunology or related discipline
Strong reputation for delivering cutting-edge research as evidenced by high impact publications
Published experience in fluorescent microscopy
Proven record of tracking and meeting goals/milestones across multiple projects
Exceptional oral and written communication skills
Must be a US citizen
Previous work with animal models and their behavioral analysis
Preference for light sheet microscopy, serial 2-photon tomography and/or imaging mass cytometry experience
Preference given for bioinformatics experience using R pipelines
Preference for flow cytometry skills and immunostaining procedures
Highly regarded as a mentor for junior and cross-discipline scientists
Functional knowledge of cytokine networks and in vivo immune cell trafficking
Proven ability to drive meaningful data visualization from large data sets and work synergistically with bioinformaticians/systems biology teams
Able to work independently as well as in a collaborative high paced environment
Internal Number: Cell001
About VA Puget Sound Health Care Center
The VA Puget Sound offers exceptional working conditions, and nurture diversity and team-science in an intellectually rich and stimulating setting. We provide a highly collaborative research environment offering the opportunity to interface closely with our molecular biologists, bioinformaticians, and partner institutions which include the University of Washington, Fred Hutchinson Cancer Research Center, Seattle Children's, the Allen Institute for Brain Science and the Institute for Systems Biology. Together we will unravel key mechanistic pathways of the human immune system across the neuroinflammatory timeline following TBI
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