The Rorabaugh laboratory at Marshall University is seeking a highly motivated Postdoctoral Research Fellow to participate in a NIH-funded project investigating the impact of prenatal exposure to methamphetamine on the adult cardiovascular system. The laboratory is particularly interested in understanding the impact of prenatal methamphetamine exposure on the adult ischemic heart. Prior work in our laboratory demonstrated that female rats that were prenatally exposed to methamphetamine develop myocardial hypersensitivity to ischemic injury when they become adults. However, hearts of their male littermates are unaffected. A similar sex-dependent effect occurs when rats are exposed to methamphetamine during early adulthood. Our laboratory is trying to understand how methamphetamine exposure during the prenatal or early adult periods sensitizes the heart to ischemic injury.
The successful candidate will be expected to participate in experimental design, conduct experiments, present research findings at scientific conferences, and prepare manuscripts for publication. Candidates should have a Ph.D. in pharmacology, physiology, neuroscience, or a related discipline and a working knowledge of cardiovascular function. Experience with rodent models of cardiac ischemic injury (Langendorff isolated heart or in vivo coronary artery ligation models) and experience with gene expression analysis (RNA sequencing, RTPCR, etc) are highly desirable. The successful candidate will have a strong publication record, exceptional communication and writing skills, and strong organizational skills.
Internal Number: R10554
About Marshall University School of Pharmacy
Marshall University is located in Huntington, West Virginia. The School of Pharmacy started in 2012, with our first class graduating in 2016. We are located on the Marshall University Health Science campus, adjacent to the Joan C. Edwards School of Medicine and Cabell Huntington Hospital.