Position Description:

A postdoctoral fellowship position is available in the Molecular Neuropharmacology Section at the National Institute of Neurological Disorders and Stroke (NINDS), NIH in Bethesda, MD.

The Sibley lab is characterizing the molecular properties and signaling mechanisms of dopamine receptors with a strong emphasis on drug discovery and development.  We leverage novel pharmacological concepts, including allosterism and biased signaling, to identify and develop receptor modulators that exhibit greater subtype and/or signaling pathway selectivity. These efforts have led to the discovery of allosteric ligands, biased agonists, and best-in-class selective agonists and antagonists of dopamine receptor subtypes. The incumbent will lead one of these projects and in the process will gain experience in cutting-edge pharmacological research.

For additional information, please visit:

https://dir.ninds.nih.gov/Faculty/Profile/david-sibley.html