A postdoctoral fellowship position is available in the Molecular Neuropharmacology Section at the National Institute of Neurological Disorders and Stroke (NINDS), NIH in Bethesda, MD.
The Sibley lab is characterizing the molecular properties and signaling mechanisms of dopamine receptors with a strong emphasis on drug discovery and development. We leverage novel pharmacological concepts, including allosterism and biased signaling, to identify and develop receptor modulators that exhibit greater subtype and/or signaling pathway selectivity. These efforts have led to the discovery of allosteric ligands, biased agonists, and best-in-class selective agonists and antagonists of dopamine receptor subtypes. The incumbent will lead one of these projects and in the process will gain experience in cutting-edge pharmacological research.
Experience in molecular/chemical biological, and/or pharmacological techniques
Previous experience with GPCRs and/or cell signaling is preferred
Self-motivated with excellent communication and writing skills
Interested candidates should submit a cover letter with their Curriculum Vitae and the names and contact information of three references to Dr. David Sibley at email@example.com. The most highly qualified candidates will be contacted with further information.
Telecommuting is allowed.
Internal Number: 705
About National Institutes of Health
The Intramural Research Program (IRP) is the internal research program of the National Institutes of Health (NIH), known for its synergistic approach to biomedical science.
With approximately 1,200 Principal Investigators and more than 4,000 Postdoctoral Fellows conducting basic, translational, and clinical research, the IRP is the largest biomedical research institution on earth.
Its unique funding environment means the IRP can facilitate opportunities to conduct both long-term and high-impact science that would otherwise be difficult to undertake.
More than 50 buildings on NIH campuses are devoted to the research enterprise, from state-of-the-art animal care facilities to homes for 7-Tesla MRIs and confocal microscopes, to a neurosciences cluster designed to foster collaborations across disciplines.